Oftalmología Marbella
Oftalmología Marbella

Diabetic retinopathy and diabetic macular oedema

retinopatía diabética ojo
 

People with diabetes are 25 times more likely to suffer blindness than the rest of the population. Fortunately, proper control of the disease and timely therapeutic action have proven to be effective in preventing this from occurring.

 

This requires the patient to be aware of his or her condition, to have a medical follow-up by a diabetes specialist, to visit the ophthalmologist regularly and to maintain a disciplined and healthy lifestyle in terms of diet, physical exercise, weight, etc. This way, an early diagnosis can be achieved and preventive action can be taken.

 
Just as the metabolic decompensation caused by diabetes affects other organs, chronic hyperglycaemia also damages the blood vessels of the retina. Diabetic retinopathy and diabetic macular oedema are the main secondary pathologies of diabetes involving retinal damage.

 
In the case of the former, the alteration of macular microcirculation can lead to a decrease in the supply of oxygen to the retina, preventing it from receiving the necessary amount for its proper functioning. This condition is known as ischaemia and can lead to the death of neuroretinal neurons. As nerve tissue does not regenerate, the damage caused is irreversible.

 

A “waterlogging” of the macula can also occur due to the alteration of the blood vessels of the macula and/or the inflammatory nature of the disease, which can lead to the leakage of intravascular fluids, causing macular oedema. This requires appropriate treatment to prevent loss of vision.

visión borrosa

Diabetic retinopathy can have other detrimental effects on vision:
 

  • Diabetic vitreous haemorrhage: new blood vessels appearing after ischaemia tend to bleed more easily, which tints the vitreous humour, compromising its transparency and leading to consequent loss of vision.
  • Tractional retinal detachment: The vitreous gel contracts when invaded by neovessels. This can displace the retina to the point of separating it from the wall of the eyeball and/or rupturing it.
  • Tractional macular oedema: Other times traction occurs gently on the macula, producing a different oedema to the one mentioned above (tractional versus vasogenic/inflammatory), as its origin is different. This oedema is not related to vascular deterioration or to the inflammatory nature of diabetes.

 
 

moscas volantes

Although the disease may not have manifested itself and remains asymptomatic, this does not mean that it is not in an advanced stage, which is why regular ophthalmological check-ups are essential. The most common symptoms are:
 

  • Gradual loss of sight
  • Blurred vision
  • Floaters
  • Poor night vision

factores de riesgo oculares

The main one is the time of evolution of diabetes, as well as not achieving good metabolic control. It is vital that diabetic patients undergo a complete ophthalmological check-up at least once a year, since poor metabolic control favours retinal lesions.

 

In addition to measuring blood glucose levels by means of a finger-prick test, the percentage of glycosylated haemoglobin should also be studied periodically. This will help us to identify any undetected hyperglycaemia.

 

There is scientific evidence that if the glycosylated haemoglobin is less than 6.9%, the incidence of diabetic retinopathy and diabetic macular oedema is reduced. However, it is also very important to avoid hypoglycaemias, which have been proven to be very harmful.

inyección intravítrea

 

The treatment of diabetic retinopathy and diabetic macular oedema requires a high degree of specialisation and state-of-the-art technology.
 

The aim of treatment will be to control the disease and slow its progression. However, it is important to remember that the best approach is the preventive one, that is, keeping diabetes, blood pressure and cholesterol levels under control, as well as following healthy lifestyles.

 
 

Laser treatment

 

Called focal treatment when it is for oedema, and panretinal photocoagulation when it is used to treat diabetic retinopathy. Argon laser treatment is very effective for advanced diabetic retinopathy, as it prevents blindness. It is an outpatient treatment performed in the doctor’s office. It can cause discomfort, reduce the field of vision and worsen night vision, but it is usually well tolerated by most patients. It requires 3 to 4 sessions for each eye.

Anti-VEGF drugs

 

Another option to treat diabetic retinopathy is the use of intraocular injections, which can also avoid many of the adverse effects of laser treatment. However, the effect is transient so it is essential that the injections, which must be administered regularly, are not interrupted. If this were to happen without supervision, the prognosis can seriously worsen. It is very important that they are supervised by an ophthalmologist with expertise in diabetes.

 
 

Treatment for diabetic macular oedema

 

Even when retinopathy is not at an advanced stage, diabetic macular oedema can cause significant vision loss. This condition is currently treated with:

 

  • Intravitreal injections using anti-VEGF drugs or corticosteroids.
  • Focal laser. Even though it does not have the relevance today that it had a few years ago, it can still be very effective for certain patients.
  • Vitreoretinal surgery: in cases where there is a tractional component or the evolution with previous treatments is unfavourable.

 

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