Dr. Trigo, José Manuel
Director of Oncology, Research and Innovation
Small cell lung cancer spreads rapidly and rarely responds well to surgery or radiotherapy, so surgery is only considered in very small tumours with no mediastinal lymphadenopathy.
However, this happens rarely, in the majority of cases small-cell lung cancer presents as an already very bulky disease (large lymphadenopathies or tumour, or both).
Patients with limited-stage small cell lung cancer (without distant metastases) are treated with a combination of chemotherapy and radiotherapy.
Radiotherapy is given during the first or second chemotherapy cycle (which lasts from three to six months). When combined with radiotherapy, the most commonly used regimen is a combination of cisplatin and etoposide. A total of 4 cycles are administered.
If there is no disease progression following chemo-radiotherapy, prophylactic brain radiotherapy is given to reduce the risk of brain metastases. This treatment would be discussed in patients over 70 years of age or who have previously had a stroke.
Patients with extensive disease (with metastases) are treated with chemotherapy only. In the case of good response to chemotherapy treatment, prophylactic brain radiotherapy or strict monitoring (approximately every 8 weeks) with brain MRI may be considered, and radiotherapy may be performed only if metastases appear.
Currently, two clinical studies have shown that combination chemotherapy and immunotherapy is more effective than chemotherapy alone in advanced small-cell lung carcinoma.
Dr. Trigo, José Manuel
Director of Oncology, Research and Innovation
Dr. Aguilar PerezGrovas, Ricardo
Neumology Specialist
Dr. Sedano Ferreras, Paula
Radiotherapy Oncology Specialist
Dr. García Baltar, José Antonio
Especialista en Radiofísica Hospitalaria
Dr. De Castro, Francisco Javier
Medical specialist in Radiology and Internal Medicine
Tel.: +34 952 908 628
+34 609 148 799
952908898 Oncology
951829978 Diagnosis by imaging
951829947 Gynecology
952908897 Fertility
951829947 Physiotherapy
